Contact infos

  • bernard.lyan{at}inrae{dot}fr
  • phone: +33(0)4 73 62 47 73

Responsible for the structural elucidation of unknown molecules by High Resolution Mass Spectrometry coupled with chromatography in nutritional studies


  • Identification of unknown molecules
  • Development of new methods
  • Trainings- Teaching Chromatography and mass spectrometry (DUT; Licence, master)


Main publications

  • Comte, B., Monnerie, S., Brandolini-Bunlon, M., Canlet, C., Castelli, F., Chu-Van, E., ... & Pujos-Guillot, E. (2021). Multiplatform metabolomics for an integrative exploration of metabolic syndrome in older men. EBioMedicine69, 103440.
    doi: 10.1016/j.ebiom.2021.103440
  • Damont, A., Olivier, M. F., Warnet, A., Lyan, B., Pujos‐Guillot, E., Jamin, E. L., ... & Fenaille, F. (2019). Proposal for a chemically consistent way to annotate ions arising from the analysis of reference compounds under ESI conditions: A prerequisite to proper mass spectral database constitution in metabolomics. Journal of Mass Spectrometry54(6), 567-582.
    doi: 10.1002/jms.4372
  • Pujos-Guillot, E., Brandolini, M., Pétéra, M., Grissa, D., Joly, C., Lyan, B., ... & Comte, B. (2017). Systems metabolomics for prediction of metabolic syndrome. Journal of proteome research16(6), 2262-2272.
    doi: 10.1021/acs.jproteome.7b00116
  • Mast, C., Lyan, B., Joly, C., Centeno, D., Giacomoni, F., Martin, J. F., ... & Papet, I. (2015). Assessment of protein modifications in liver of rats under chronic treatment with paracetamol (acetaminophen) using two complementary mass spectrometry-based metabolomic approaches. Journal of proteomics120, 194-203.
    doi: 10.1016/j.jprot.2015.03.014
  • Lyan, B., Azaı̈s-Braesco, V., Cardinault, N., Tyssandier, V., Borel, P., Alexandre-Gouabau, M. C., & Grolier, P. (2001). Simple method for clinical determination of 13 carotenoids in human plasma using an isocratic high-performance liquid chromatographic method. Journal of Chromatography B: Biomedical Sciences and Applications751(2), 297-303.
    doi: 10.1016/S0378-4347(00)00488-6