Contact infos

  • michel.hebraud{at}inrae{dot}fr
  • phone: +33(0)4 73 62 46 70

My main research fields are the physiology of pathogenic bacteria in biofilms, their resistance/adaptation to environmental and technological stresses in food processing plants and the development of novel surface decontamination strategies. To decipher bacterial molecular mechanisms, I use in particular proteomic approaches.


  • Deputy Director of the Research Support Unit UAR1140, head of the Commission Nationale des Outils Collectifs INRAE (CNOC), in charge of the annual calls for tenders for heavy equipment / medium-sized equipment, the labelling of collective scientific infrastructures (ISC) of the "Analytical Platform" type and the three-yearly strategic and budgetary dialogues with the ISCs, member of the Bureau des Infrastructures de Recherche (BIR) and of the Commission Nationale des Engagements (CNE).
  • Scientific head of the proteomic component of the PFEM.
  • Research Director in the UMR0454 UCA-INRAE Microbiology, Digestive Environment and Health (MEDiS).


Main publications
(Web of Science ResearcherID D-1009-2009, ORCID ID 0000-0003-0478-2575)

  • Santos, T., & Hébraud, M. (2021). Extraction and Preparation of Listeria monocytogenes Subproteomes for Mass Spectrometry Analysis. In Listeria Monocytogenes (pp. 137-153). Humana, New York, NY.
  • Santos, T., Viala, D., Chambon, C., Esbelin, J., & Hébraud, M. (2019). Listeria monocytogenes biofilm adaptation to different temperatures seen through shotgun proteomics. Frontiers in nutrition6, 89.
  • Esbelin, J., Santos, T., Ribière, C., Desvaux, M., Viala, D., Chambon, C., & Hébraud, M. (2018). Comparison of three methods for cell surface proteome extraction of Listeria monocytogenes biofilms. Omics: a journal of integrative biology22(12), 779-787.
  • Santos, T., Théron, L., Chambon, C., Viala, D., Centeno, D., Esbelin, J., & Hébraud, M. (2018). MALDI mass spectrometry imaging and in situ microproteomics of Listeria monocytogenes biofilms. Journal of proteomics187, 152-160.
  • Esbelin, J., Santos, T., & Hébraud, M. (2018). Desiccation: an environmental and food industry stress that bacteria commonly face. Food microbiology69, 82-88.
  • Azeredo, J., Azevedo, N. F., Briandet, R., Cerca, N., Coenye, T., Costa, A. R., ... & Sternberg, C. (2017). Critical review on biofilm methods. Critical reviews in microbiology43(3), 313-351.
  • Giaouris, E., Heir, E., Desvaux, M., Hébraud, M., Møretrø, T., Langsrud, S., ... & Simões, M. (2015). Intra-and inter-species interactions within biofilms of important foodborne bacterial pathogens. Frontiers in microbiology6, 841.